The Team Behind Sierra Advanced Medicine

Anji Ruppert, MSN, ACNP

Founder, Nurse Practitioner

Anji is a board-certified Acute Care Nurse Practitioner with a dual Bachelor’s degree in Biology and Nursing, and a Master’s degree in Nursing from the University of Nevada, Reno. She began her career in high-acuity medicine, working in critical care, emergency medicine, and as a Certified Flight Registered Nurse (CFRN), serving as a first responder flight nurse for over seven years. This experience built the foundation for her clinical precision, critical thinking, and unwavering commitment to patient safety.

Driven by a passion for advancing beyond traditional medicine, Anji has dedicated extensive time to advanced training in hormone optimization, bioidentical hormone replacement therapy (BHRT), and functional endocrinology. She is board certified in Advanced Endocrinology through the American Academy of Anti-Aging Medicine and is among a select group of providers in Northern Nevada certified in both Menopause and Andropause management. Her commitment to continued education ensures her patients receive the most current, evidence-based care in longevity and precision medicine.

Anji’s approach to medicine is rooted in identifying and addressing the root cause of symptoms, and optimizing health. She specializes in optimizing hormones, metabolic health, and overall wellness through integrating conventional and functional medicine. Her goal is to help patients feel energized, balanced, and fully aligned in their health at every stage of life.

In addition to her medical practice, Anji offers natural aesthetic treatments designed to complement internal health. Her philosophy is centered on subtle, refined enhancements which restore confidence and highlight each patient’s natural beauty—never overdone.

A proud Reno native, Anji is deeply committed to her community and to elevating the standard of care through personalized, advanced medicine. Outside of the clinic, she enjoys spending time with her family, loved ones, and her dog, often exploring the beauty of the Sierra or enjoying her pontoon boat.

Riley Henderson, MSN, FNP

Nurse Practitioner, Medical Aesthetic Provider

Riley Henderson is a board-certified Family Nurse Practitioner with over a decade of experience in healthcare. A Reno native and proud graduate of the University of Nevada, Reno, she earned her Bachelor of Science in Nursing and later completed her Family Nurse Practitioner degree. Her diverse clinical background includes oncology, gastroenterology, infusion therapy, primary care, and medical aesthetics, providing a well-rounded foundation rooted in safety, clinical excellence, and evidence-based practice.

Throughout her career, Riley has been committed to advancing her clinical knowledge and skill set through continued education and hands-on training. She has pursued advanced training in aesthetic medicine and has trained with some of the leading minds in medical aesthetics. Her approach reflects a balance of science and artistry, with an emphasis on delivering thoughtful, results-driven treatments tailored to each individual.

Riley believes aesthetic medicine should enhance—not change—who you are. She prioritizes natural, balanced results, honest recommendations, and patient education, ensuring every treatment plan is both personalized and aligned with each patient’s goals. Her goal is to create a supportive, transparent environment where patients feel confident in their care and empowered in their decisions. In addition to aesthetics, Riley is passionate about helping patients optimize their overall health, integrating wellness principles into her approach whenever appropriate.

Outside of the clinic, Riley enjoys spending time with her husband and two sons, traveling, staying active, reading, and exploring the outdoors.

About Sierra Advanced Medicine

Reno/Tahoe’s Integrative Medicine & Medical Aesthetics Practice

Anji Ruppert Founder Sierra Advanced Medicine Reno Tahoe
About Sierra Advanced Medicine : Founded by Nurse Practitioner Anji Ruppert in 2026, Sierra Advanced Medicine represents the culmination and evolution of her previous practices—bringing together years of experience in hormone optimization, integrative medicine, and aesthetic care into one cohesive, elevated model of healthcare.

Sierra Advanced Medicine was created to redefine the traditional medical experience. It was built on the belief that patients deserve to be heard, their concerns taken seriously, and their care approached with a comprehensive, whole-person perspective—not reduced to isolated symptoms or rushed visits.

Serving the Reno/Tahoe area, we combine integrative, evidence-based medicine with aesthetic expertise, guided by advanced diagnostics and a highly personalized approach. Every recommendation is grounded in clinical insight, precision, and a comprehensive understanding of the factors that influence health, longevity, and aging.

We believe exceptional results—both in wellness and aesthetics—come from addressing the whole person. From comprehensive lab evaluations and hormone optimization to skin rejuvenation and aesthetic treatments, each service is designed to work in harmony, supporting internal health and outward confidence.

Every treatment plan is tailored to your goals, your physiology, and your long-term vision for your health. Our patients aren’t looking for quick fixes—they’re seeking clarity, optimization, and a trusted partner in their care. That’s exactly what we provide: intentional, personalized medicine designed to help you feel your best, look your best, and support long-term vitality.

Personalized health care starts here.

775.219.3655